🔬 KPV Peptide (Oral Formulation) – For Research Use Only

🧪 Chemical Profile

• Name: KPV (Lys-Pro-Val)

• Sequence: Lysine–Proline–Valine (tripeptide)

• Molecular Formula: C₁₅H₂₈N₆O₄

• CAS Number: 3640-58-8

⚙️ Mechanism & Research Applications

• KPV is a bioactive tripeptide derived from the alpha-melanocyte stimulating hormone (α-MSH) with anti-inflammatory and immunomodulatory properties demonstrated in vitro and in vivo.

• Investigated for potential therapeutic effects in inflammatory bowel disease, dermatitis, and other inflammatory conditions via modulation of macrophage activity and cytokine release.

• Oral delivery research is ongoing; peptide stability and absorption in the GI tract remain under study.

🔬 Oral Bioavailability & Administration

• Oral bioavailability is limited due to enzymatic degradation in the digestive system.

• Formulations often include protective delivery systems (e.g., enteric coatings) to enhance stability and absorption in research models.

• Dosing in animal studies varies widely; no established human dosing or clinical approval exists.

⚠️ Safety & Regulatory Status

• KPV is not FDA-approved for human or veterinary use.

• Supplied exclusively for laboratory research and must be clearly labeled:

  “For research use only. Not for human or veterinary use.”

• Safety profile in humans is not fully characterized; use caution in handling and administration.