BAM15 (Mitochondrial Uncoupler) – High-Purity Research Compound

CAS Number: 14005-41-9
Other Names: BAM-15, BAM 15, BAM15 uncoupler, N⁵,N⁶-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine
Molecular Formula: C₁₄H₉F₂N₅O
Molecular Weight: 301.25 g/mol
Form: High-purity Powder
Concentration Options: Custom mg per unit (Inquire for Aliquot, Bulk, or Capsule)
Intended Use: Laboratory and Scientific Research Only

BAM15 is a mitochondrial protonophore and selective uncoupler of oxidative phosphorylation, investigated for its effects on mitochondrial bioenergetics, obesity models, and metabolic health pathways. Unlike traditional uncouplers like DNP, BAM15 has been found to uncouple mitochondria without altering the mitochondrial membrane potential, making it a novel compound in metabolic and obesity-related research.

At Combat Research, we supply research-grade BAM15 for use in:

• Mitochondrial uncoupling studies

• Obesity and metabolic disease models (non-human)

• Bioenergetics, ATP modulation, and ROS balance

• Thermogenic and energy expenditure research

🔬 Scientific Publications & Research References

BAM15 is actively studied in the fields of metabolism, aging, and cellular respiration. Below are peer-reviewed publications and relevant research:

• Alexandre K. et al. (2020). BAM15 reduces body weight, adiposity, and insulin resistance in high-fat diet-fed mice. Nature Communications.
  https://doi.org/10.1038/s41467-020-19776-7

• Kenwood BM, et al. (2014). Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane. Molecular Metabolism.
  https://doi.org/10.1016/j.molmet.2014.03.005

• NIH on Mitochondrial Therapeutics: https://pubmed.ncbi.nlm.nih.gov/?term=BAM15

⚠️ NOT FOR HUMAN OR VETERINARY USE – RESEARCH ONLY

This product is provided strictly for laboratory research and in vitro use only. BAM15 is not approved by the U.S. Food and Drug Administration (FDA) for use in food, drugs, medical devices, or cosmetic applications.

Not for human or animal consumption. Do not ingest, inhale, inject, or apply to skin. This compound is intended only for use by qualified professionals in legally licensed research laboratories.

Users must comply with all local, state, and federal regulations regarding chemical handling and safety.

Each unit is packaged in sealed, batch-verified containers. Certificates of Analysis (COA), Safety Data Sheets (SDS), and Quality Control reports are available upon request.