🧪 Sermorelin Acetate — Research Peptide

Chemical Name: Sermorelin Acetate
CAS Number: 86168-78-7
Synonyms: GHRH (1-29) NH₂, Sermorelin, Growth Hormone–Releasing Hormone Fragment (1-29), GHRH-29
Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₅S
Molecular Weight: ≈ 3357.9 Da

🔬 Overview

Sermorelin Acetate is a synthetic peptide analogue corresponding to the first 29 amino acids of endogenous growth hormone–releasing hormone (GHRH).
It functions as a GHRH receptor agonist and is studied in research settings to evaluate pituitary signaling, GH regulation, and peptide pharmacodynamics.

Regulatory Status:
Sermorelin Acetate is not approved by the U.S. Food and Drug Administration (FDA) for general human use or as a dietary supplement.
It is available for research and investigational purposes only and should not be marketed as a therapeutic or cosmetic product.

⚗️ Chemical & Physical Properties

📘 Research Context (Preclinical Literature)

The information below is based on laboratory and clinical pharmacology studies. It is not intended as medical advice or an endorsement of therapeutic use.

• Sermorelin has been used in pituitary function research to stimulate endogenous GH release and evaluate hypothalamic–pituitary axis function.
  – PubMed: 6433617

• Studies demonstrate dose-dependent GH release following Sermorelin administration in animals and humans under controlled research settings.
  – PubMed: 3182193

• Investigations also explore the peptide’s short half-life, receptor binding profile, and downstream effects on IGF-1 in endocrine models.
  – PubMed: 2864485

⚠️ These findings have not been evaluated or approved by the FDA for clinical or consumer use.

⚠️ Regulatory & Compliance Statement

• For Research Use Only.

• Not for Human or Veterinary Use.

• Not an FDA-approved drug, cosmetic, or dietary supplement.

• Intended solely for in vitro, laboratory, or preclinical animal model studies.

• No claims are made regarding treatment, cure, or prevention of disease.

🧴 Recommended Label Example (Compliant Text)

Product: Sermorelin Acetate
CAS: 86168-78-7
Purity: ≥98% (HPLC)
Form: Lyophilized powder
Intended Use: For scientific research use only. Not for human consumption or injection.
Storage: Store frozen at –20 °C. Avoid direct light and moisture exposure.

🔍 SEO & Keyword Optimization (Compliant Terms)

Use only factual, non-medical descriptors to improve search visibility without implying unapproved use.

Primary Keywords:
Sermorelin research peptide, Sermorelin Acetate CAS 86168-78-7, GHRH 1-29 peptide, Sermorelin molecular formula, growth hormone releasing hormone fragment research, pituitary peptide study, Sermorelin pharmacology research

Secondary Keywords:
Sermorelin peptide information, GHRH analogue peptide, research peptide USA, laboratory peptide supplier

📚 Suggested Reference Links (for “Further Reading”)

1. Thorner MO, et al. Human growth hormone–releasing factor stimulates GH secretion in man. J Clin Endocrinol Metab. 1984;58(2):319-325. PubMed: 6433617

2. Rivier J, Spiess J, Vale W. Characterization of a 29-amino acid synthetic peptide corresponding to the biologically active region of GHRH. Science. 1983;219(4585):409-411. PubMed: 6185956

3. Vance ML, et al. Pharmacokinetic and endocrine studies of Sermorelin (GRF 1-29-NH₂) in normal subjects. J Clin Endocrinol Metab. 1985;60(6):1212-1219. PubMed: 2864485

✅ Summary (Website / Catalog Boilerplate)

Sermorelin Acetate (CAS 86168-78-7) is a synthetic peptide analogue of growth hormone-releasing hormone used in research to explore GH regulation and pituitary receptor pathways. This material is supplied for scientific and laboratory use only and is not approved by the FDA for human use. All product information is for educational and research purposes.