🔬 MK‑677 (Ibutamoren) Injectable – For Research Use Only

Chemical Identity:

• Name: Ibutamoren mesylate (aka MK‑677, MK‑0677)

• CAS #: 159634‑47‑6

• Molecular Formula: C₁₄H₁₂F₆N₂O (mesylate salt variant) reddit.com+15ironmountainlabz.com+15combatresearch.io+15androgenixsolutions.com+2en.wikipedia.org+2mncdhh.org+2

Pharmacological Profile:

• Agonist of the ghrelin receptor (GHS‑R1a), promoting endogenous GH and IGF‑1 secretion.

• Oral form studied extensively; injectable aims for higher and faster bioavailability (~80–100%) compared to oral (~60–70%) cochrane-handbook.org+15dailyuw.com+15en.wikipedia.org+15combatresearch.io.

• Half-life supports once-daily dosing; effects on GH secretion observed hours post-dose .

Intended Use:

• For in vitro or animal model research within licensed facilities.

• Not approved by the FDA for human clinical use or consumption.

• Distribution or use in humans constitutes unapproved drug use.

Formulation & Handling:

• Provided as a sterile, injectable solution at research-grade purity (≥98% HPLC).

• Typical concentration: 25–50 mg/mL in bacteriostatic water reddit.com+9combatresearch.io+9dailyuw.com+9.

• Suggested starting dose (research settings): 10–25 mg/day subcutaneously, daily or every-other-day injection. Adjust based on study protocol reddit.com+3combatresearch.io+3reddit.com+3.

Potential Research Benefits:

• ↑ Growth hormone & IGF‑1 levels—sustains pulses without suppressing testosterone cochrane-handbook.org+15en.wikipedia.org+15reddit.com+15.

• Promotes lean muscle mass, bone mineral density, sleep quality, and tissue recovery in clinical studies peptideresearcher.com+5aaiclinics.com+5en.wikipedia.org+5.

• Higher bioavailability from injectable may enhance receptor activation and physiological responses reddit.com+12combatresearch.io+12ironmountainlabz.com+12.

Known Side Effects (from oral/injectable studies):

• Increased appetite and potential weight gain reddit.com+5reddit.com+5reddit.com+5.

• Fluid retention, mild edema in extremities mncdhh.org.

• Numbness, joint/muscle discomfort, transient lethargy .

• Monitor blood glucose and insulin due to potential insulin resistance .

• Avoid in subjects with active cancers—IGF‑1 may promote tumor growth cochrane-handbook.org+15mncdhh.org+15en.wikipedia.org+15.

Storage & Safety:

• Store refrigerated at 2–8 °C; protect from light.

• Use aseptic technique; single-use vials preferred.

• PPE required: gloves, lab coat, eye protection.

• Dispose of needles/storage per institutional biohazard protocols.