Abstract
5-Amino 1 (5-Amino-1MQ) is a small-molecule compound currently under investigation for its potential effects on energy metabolism, fat oxidation, and NAD+ regulation. Recent preclinical studies suggest that 5-Amino 1 may inhibit the enzyme N-methyltransferase (NNMT), potentially improving cellular energy homeostasis and lipid metabolism. This injectable form is designed strictly for controlled laboratory research and in vitro applications.
Chemical Information
- Compound Name: 5-Amino-1MQ
- Chemical Formula: C7H11N5
- Molecular Weight: 165.19 g/mol
- CAS Number: 1800101-53-8
- Form: Injectable research solution (20 mL)
- Concentration: Variable, for controlled research use only
Mechanism of Action
5-Amino 1 acts as a selective NNMT inhibitor, a key enzyme involved in methylation and NAD+ metabolism. By downregulating NNMT activity, this compound may promote increased intracellular NAD+ levels, potentially supporting enhanced mitochondrial activity, fat metabolism, and energy balance in cell-based models.
Studies have shown that NNMT inhibition may correlate with improved insulin sensitivity and reduced adipogenesis in preclinical systems.
- PubMed: NNMT inhibition and metabolic improvement
- PubMed: Role of NNMT in metabolic regulation
- PubMed: NAD+ metabolism and cellular energy
Potential Research Applications
- Metabolic Research: To explore the effects on NNMT activity and NAD+ levels.
- Obesity Models: Assessing adipocyte differentiation and lipid storage.
- Cellular Energy Studies: Evaluating ATP and NAD+ production pathways.
- Mitochondrial Function: Investigating mitochondrial respiration and oxidative stress.
- Aging Research: Examining cellular senescence and methylation balance.
Key SEO & Research Keywords
5-Amino 1MQ injectable, NNMT inhibitor, NAD+ enhancer, fat metabolism, metabolic regulation, mitochondrial function, adipogenesis, energy homeostasis, research peptide, Combat Research, laboratory use only.
Dosage & Handling (For Research Use Only)
- Formulation: Sterile injectable solution
- Storage: 2–8°C, protected from light
- Use: Designed solely for controlled in vitro or animal-based research models.
- Not for human use.
Safety and Handling
Researchers must adhere to standard laboratory safety protocols. Protective gloves, eyewear, and sterile instruments are required during handling.
Do not inject into humans or animals outside approved research environments.
10 Common Research FAQs
1. What is 5-Amino 1 used for in research?
It’s primarily studied for its potential to regulate NNMT and NAD+ metabolism in energy and obesity-related models.
2. Is 5-Amino 1 similar to peptides like CJC-1295 or BPC-157?
No, it is a small-molecule compound, not a peptide.
3. Can 5-Amino 1 be taken orally?
For research, it’s formulated as an injectable for accurate dosing and bioavailability studies.
4. What are the main research benefits observed?
Preclinical findings include potential improvements in fat oxidation and cellular energy efficiency.
5. What type of research models is it used in?
It’s typically used in rodent and in vitro cell line models.
6. How is it stored?
Store at 2–8°C and protect from light and contamination.
7. Does 5-Amino 1 affect NAD+ levels directly?
It may indirectly increase NAD+ by inhibiting NNMT, a methylation enzyme that consumes NAD+ precursors.
8. Are there human trials?
Currently, no FDA-approved human clinical trials are available.
9. Can it be combined with other research agents?
Combination research must be justified by institutional protocols.
10. Is it legal to sell or use in humans?
No, it’s for research use only, not approved for human consumption or therapeutic use.
Research Disclaimer
This product is intended for laboratory research purposes only. It is not approved by the FDA for human or veterinary use. All statements herein are for informational and educational purposes for qualified researchers. Misuse of this compound outside of research contexts is strictly prohibited.
